Loddo, Roberta and Briguglio, Irene and Corona, Paola and Piras, Sandra and Loriga, Mario and Paglietti, Giuseppe and Carta, Antonio and Sanna, Giuseppina and Giliberti, Gabriele and Ibba, Cristina and Farci, Pamela and La Colla, Paolo (2014) Synthesis and antiviral activity of new phenylimidazopyridines and N-benzylidenequinolinamines derived by molecular simplification of phenylimidazo[4,5-g]quinolines. European Journal of Medicinal Chemistry, Vol. 84 , p. 8-16. ISSN 0223-5234. Article.
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Continuing our program of research concerning the antiviral activity of a wide series of new angular and linear azolo bicyclic and tricyclic derivatives, now we have simplified and modified the 4-chloro-2-(4-nitrophenyl)-3H-imidazo[4,5-g]quinoline 1, which previously resulted the most active derivative, through either the elimination of the central ring or the opening of the imidazole ring, obtaining various imidazopyridines and Nbenzylidenequinolinamines respectively.
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