Dore, Stefano and Devilla, L. and Salvo, Marco Michele and Dessole, Laura and Patteri, Pierpaolo (2007) Thrombophlebitis and bilateral visual loss and in Behçet’s disease. Acta Ophthalmologica, Vol. 85 (Suppl. s240). ISSN 1755-375X. eISSN 1755-3768. Article.
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Purpose: To describe an unusual case of Behçet’s disease characterized by bilateral ocular involvement and thrombophlebitis in the right leg.
Methods: A 37-year-old man was referred with a two-month history of progressive, severe visual loss in both eyes. He had had thrombophlebitis in his right leg following an insect bite a month before. Visual acuity was R.E.: light perception and L.E.: 20/400. Fundus examination disclosed bilateral papillitis and retinal vasculitis and a macular pucker in the right eye.
Results: Fluorescein angiography showed occlusive arteritis with periphlebitis in both eyes. TC and MR imaging and laboratory tests for toxoplasmosis, Lyme disease, syphilis, HIV, HSV, and Rickettsia conorii infection were negative. Conversely, ESR, PCR and HLA-B51 were found to be positive. Treatment with systemic steroids produced no improvement.
Conclusions: Ocular Behçet’s disease is occasionally not associated with the classic systemic signs, such as oral aphtous lesions, skin lesions, and genital lesions. In this report, the retinal lesions followed an episode of thrombophlebitis caused by an insect bite.
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