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Primary orbital eosinophilic angiocentric fibrosis with intranasal extension

Karligkiotis, Apostolos and Volpi, Luca and Ferreli, Fabio and Cerati, Michele and Kagkelari, Effrosyni and Meloni, Francesco and Castelnuovo, Paolo (2014) Primary orbital eosinophilic angiocentric fibrosis with intranasal extension. Head & neck, Vol. 36 (1). ISSN 1043-3074. eISSN 1097-0347. Article.

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DOI: 10.1002/hed.23396

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Abstract

Background. Eosinophilic angiocentric fibrosis is a chronic, idiopathic disorder that usually involves the upper respiratory tract and features progressive submucosal perivascular fibrosis of unknown etiology. To our knowledge, only 5 cases of eosinophilic angiocentric fibrosis with primary orbital involvement have been reported.
Methods and Results. We report the case of a 46-year-old man with right proptosis and lateral globe displacement caused by a primary eosinophilic angiocentric fibrosis extending from the orbit into the anterior ethmoid. The nasal extension of the lesion helped in establishing the correct diagnosis.
Conclusion. Physicians involved in the treatment of orbital pathologies should be familiar with this entity, because it may manifest as an intraorbital mass growing primarily or secondly into the orbit. The clinical manifestations of eosinophilic angiocentric fibrosis with orbital involvement often mimic other more common ophthalmological diseases. Biopsies are necessary for diagnosis and treatment planning, although cures are usually of palliative effect.

Item Type:Article
ID Code:9967
Status:Published
Refereed:Yes
Uncontrolled Keywords:Eosinophilic angiocentric fibrosis, orbit, onion-skin pattern, endoscopic sinus surgery, sinonasal tract
Subjects:Area 06 - Scienze mediche > MED/31 Otorinolaringoiatria
Divisions:001 Università di Sassari > 01-a Nuovi Dipartimenti dal 2012 > Scienze Chirurgiche, Microchirurgiche e Mediche
001 Università di Sassari > 03 Istituti > Oftalmologia, Otorinolaringoiatria e Urologia
Publisher:Wiley
ISSN:1043-3074
eISSN:1097-0347
Deposited On:15 Jul 2014 09:51

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