Cirrone, G.G.P. and Cuttone, Giacomo and Candiano, Giuliana and Di Rosa, F. and Lo Nigro, Salvatore and Lo Presti, Domenico and Randazzo, Nunzio and Sipala, Valeria and Bruzzi, Mara and Menichelli, David and Scaringella, Monica and Bashkirov, Vladimir A. and Williams, R.D. and Sadrozinski, Hartmut F.W. and Heimann, Jason and Feldt, Jason and Blumenkrantz, Nate and Talamonti, Cinzia and Schulte, Reinhard (2007) Monte Carlo Studies of a proton computed tomography system. IEEE Transactions on Nuclear Science, Vol. 54 (5), p. 1487-1491. ISSN 0018-9499. eISSN 1558-1578. Article.
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Proton therapy is a precise forms of radiation therapy that makes use of high energy proton compared to the conventional, more commonly used and less precise x-ray and electron beams. On the other hand, to fully exploit the proton therapy advantages, very accurate quality controls of the treatments are required. These are mainly related to the dose calculations and treatment planning. Actually dose calculations are routinely performed on the basis of X-ray computed tomography while a big improvement could be obtained with the direct use of protons as the imaging system. In this work we report the results of Monte Carlo simulations for the study of an imaging system based on the use of high energy protons: the proton computed tomography (pCT). The main limitation of the pCT and the current adopted technical solutions, based on the use of the most likely path (MLP) approximation are illustrated. Simulation results are compared with experimental data obtained with a first prototype of pCT system tested with 200 MeV proton beams available at the Loma Linda University Medical Center (LLUMC) (CA).
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