titoli, abstracts, parole chiave >>>
Preneoplastic and neoplastic gallbladder lesions occasionally discovered after elective videocholecystectomy for benign disease A single centre experience and literature review

Paliogiannis, Panagiotis and Scognamillo, Fabrizio and Attene, Federico and Marrosu, Antonio and Trignano, Emilio and Tedde, Laura and Delogu, Daniele and Trignano, Mario (2013) Preneoplastic and neoplastic gallbladder lesions occasionally discovered after elective videocholecystectomy for benign disease A single centre experience and literature review. Annali italiani di chirurgia (in press). ISSN 0003-469X. Article.

Full text not available from this repository.

Alternative URLs:

Abstract

INTRODUCTION: In this study we retrospectively reviewed data on 311 consecutive elective cholecystectomies, performed for benign disease (cholelithiasis, cholecystitis) in our institution in the last six years, in order to determine the frequency of unexpected gallbladder pre-neoplastic and neoplastic lesions and analyse their clinical, diagnostic and therapeutic features.
MATERIALS AND METHODS: Three hundred eleven consecutive patients underwent elective cholecystectomy for benign gallbladder disease in our Institution from January 2005 to March 2011. Clinical records and histo-pathological reports were reviewed in order to detect occult gallbladder pre-neoplastic and neoplastic lesions and describe the clinical, diagnostic and therapeutic findings. Eight patients were excluded for lacking of important clinical data.
RESULTS: Out of 303 patients examined, 26 (8.6%) were found to be affected by a concomitant pre-neoplastic or neoplastic lesion. Ten (3.3%) were found to have a benign lesion, 13 (4.3%) a dysplasia of the gallbladder epithelium and 3 (1%) a gallbladder adenocarcinoma.
DISCUSSION: Dysplasia was found in 4,3% of cases and surgery represents the interruption of an eventual malignant evolution. Adenomiomatosis and adenomas represent the most frequent benign occult lesions discovered; surgery is the definitive cure for such lesions. Occult gallbladder adenocarcinoma was detected in 1% of cases in absence of any preoperative clinical or radiological suspect. Cholecystectomy is curative in stage T1a disease, while a re-resection is necessary for more invasive non metastatic disease.

Item Type:Article
ID Code:9544
Status:In Press
Refereed:Yes
Uncontrolled Keywords:Cholecystectomy, cholelithiasis, dysplasia, gallbladder cancer, gallbladder stones
Subjects:Area 06 - Scienze mediche > MED/18 Chirurgia generale
Divisions:001 Università di Sassari > 01-a Nuovi Dipartimenti dal 2012 > Scienze Chirurgiche, Microchirurgiche e Mediche
Publisher:Edizioni Luigi Pozzi
ISSN:0003-469X
Deposited On:17 Dec 2013 08:55

I documenti depositati in UnissResearch sono protetti dalle leggi che regolano il diritto d'autore

Repository Staff Only: item control page