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The Genetic legacy of Palaeolithic Homo sapiens sapiens in extant Europeans: a Y-chromosome perspective

Semino, Ornella and Passarino, Giuseppe and Oefner, Peter and Lin, Alice A. and Arbuzova, Svetlana and Beckman, Lars E. and De Benedictis, Giovanna and Francalacci, Paolo and Kouvatsi, Anastasia and Limborska, Svetlana Andreevna and Marcikiæ, Mladen and Primorac, Dragan and Santachiara-Benerecetti, Silvana A. and Cavalli-Sforza, Luca and Underhill, Peter A. (2000) The Genetic legacy of Palaeolithic Homo sapiens sapiens in extant Europeans: a Y-chromosome perspective. Science, Vol. 290 (5494), p. 1155-1159. eISSN 1095-9203. Article.

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DOI: 10.1126/science.290.5494.1155


A genetic perspective of human history in Europe was derived from 22 binary markers of the nonrecombining Y chromosome (NRY). Ten lineages account for >95% of the 1007 European Y chromosomes studied. Geographic distribution and age estimates of alleles are compatible with two Paleolithic and one Neolithic migratory episode that have contributed to the modern European gene pool. A significant correlation between the NRY haplotype data and principal components based on 95 protein markers was observed, indicating the effectiveness of NRY binary polymorphisms in the characterization of human population composition and history.

Item Type:Article
ID Code:9523
Uncontrolled Keywords:Nonrecombining Y chromosome (NRY), modern European gene pool, NRY binary polymorphisms, human population composition
Subjects:Area 05 - Scienze biologiche > BIO/18 Genetica
Divisions:001 Università di Sassari > 01-a Nuovi Dipartimenti dal 2012 > Storia, Scienze dell'Uomo e della Formazione
Publisher:American Association for the Advancement of Science
Deposited On:04 Dec 2013 09:47

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