Fiori, Pier Luigi and Diaz, Nicia Maria Luisa Eugenia and Cocco, Anna Rita and Rappelli, Paola and Dessì, Daniele (2013) Association of Trichomonas vaginalis with its symbiont Mycoplasma hominis synergistically upregulates the in vitro proinflammatory response of human monocytes. Sexually Transmitted Infections, Vol. 89 (6), p. 449-454. ISSN 1368-4973. eISSN 1472-3263. Article.
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Objectives Trichomonas vaginalis is the causative agent of trichomoniasis, one of the most common sexually transmitted diseases worldwide. In recent years we have described the symbiotic relationship between T. vaginalis and Mycoplasma hominis. How this biological association might affect the pathogenicity of one or both the microorganisms is still unknown. Since local inflammation is thought to play a central role in T. vaginalis infection, we investigated the in vitro response of human macrophages to naturally mycoplasma-free T. vaginalis, as compared to a mycoplasma-infected trichomonad isolate.
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