Delitala, Alessandro Palmerio (2014) L’Asse ipotalamo-ipofisi GH-IGF-1 nel diabete mellito di tipo 2 e nel LADA: ruolo dell’adiponectina. Doctoral Thesis.
Introduction: Growth hormone (GH) neurosecretion is often impaired in patients with diabetes mellitus. GH secretion is reduced in patient with type 2 diabetes mellitus (T2D), whereas is normal - or even enhanced - in patients with type 1 diabetes mellitus. Less is known in latent autoimmune diabetes in adults (LADA) patients. Differences in adipose tissue distribution may partly account for these findings. The dysregulated expression of various bioactive substances secreted by adipose tissue are clearly linked to metabolic diseases. Moreover, these adipokines can alter anterior pituitary function and may contribute to a dysregulation of the GH-IGF-1 axis.
I documenti depositati in UnissResearch sono protetti dalle leggi che regolano il diritto d'autore
Repository Staff Only: item control page