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Lithiation of 4-membered heterocycles as useful strategy for the preparation of new molecular scaffolds: addressing the regioselectivity in azetidines and thietanes

Degennaro, Leonardo and Zenzola, Marina and Trinchera, Piera and Carroccia, Laura and Giovine, Arianna and Falcicchio, Aurelia and Pisano, Luisa and Luisi, Renzo (2013) Lithiation of 4-membered heterocycles as useful strategy for the preparation of new molecular scaffolds: addressing the regioselectivity in azetidines and thietanes. In: 35. Convegno della Divisione di chimica organica della Società Chimica Italiana, 9-13 settembre 2013, Sassari, Italia. [S.l.], Società Chimica Italiana, Divisione di chimica organica. F13/P78. Conference or Workshop Item.

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Abstract

Four-membered heterocycles (4-MH) with one or two heteroatoms are of great importance in medicinal chemistry and synthetic organic chemistry. This kind of scaffolds show peculiar structural features, related to the ring “puckering”, and biological properties. Our recent research efforts have been focused on the stereoselective synthesis and functionalization of some 4-MH such as azetidines, thietanes and oxazetidines.

Item Type:Conference or Workshop Item (Poster)
ID Code:9286
Status:Published
Uncontrolled Keywords:Molecular scaffolds, azetidines, thietanes, medicinal chemistry, synthetic organic chemistry
Subjects:Area 03 - Scienze chimiche > CHIM/06 Chimica organica
Divisions:001 Università di Sassari > 01-a Nuovi Dipartimenti dal 2012 > Chimica e Farmacia
Publisher:Società Chimica Italiana, Divisione di chimica organica
Publisher Policy:Depositato per gentile concessione dell'Editore
Deposited On:05 Nov 2013 07:55

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