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Ex vivo cutaneous penetration of econazole nitrate from SLN incorporated in hydrophilic gels

Canu, Giacomina and Sanna, Vanna Annunziata and Gavini, Elisabetta and Cossu, Massimo and Rassu, Giovanna and Giunchedi, Paolo (2006) Ex vivocutaneous penetration of econazole nitrate from SLN incorporated in hydrophilic gels. In: SardiniaChem 2006: giornata di studio dedicata alla chimica organica delle molecole biologicamente attive, 5 giugno 2006, Cagliari, Italia. Conference or Workshop Item.

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Abstract

Solid lipid nanoparticles (SLN) are considered as innovative drug carrier for topical application. The small size of the lipid particles ensures close contact to the stratum corneum and can increase the amount of the drug penetrating into the skin and it allows controlled drug release. The aim of this study was to develop controlled release gels containing SLN dispersions loaded with Econazole Nitrate (ECN) and to evaluate ex vivo skin penetration of the drug released from the particles.

Item Type:Conference or Workshop Item (Poster)
ID Code:908
Status:Published
Uncontrolled Keywords:Solid lipid nanoparticles, Econazole nitrate, topical drugs, gels
Subjects:Area 03 - Scienze chimiche > CHIM/09 Farmaceutico tecnologico applicativo
Divisions:001 Università di Sassari > 01 Dipartimenti > Scienze del farmaco
Additional Information:Comitato organizzatore di SardiniaChem 2006: Salvatore Cabiddu, Pier Paolo Piras Università di Cagliari; Giovanna Delogu, CNR Sassari; Giampaolo Giacomelli, Università di Sassari.
Deposited On:18 Aug 2009 10:03

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