Spadafora, Natasha D. and Perrotta, Lara and Nieuwland, Jeroen and Albani, Diego Maria and Bitonti, Maria Beatrice and Herbert, Robert J. and Doonan, John H. and Marchbank, Angela M. and Siciliano, Ilario and Grønlund, Anne Lentz and Francis, Dennis and Rogers, Hilary J. (2012) Gene dosage effect of WEE1 on growth and morphogenesis from arabidopsis hypocotyl explants. Annals of Botany, Vol. 110 (8), p. 1631-1639. eISSN 1095-8290. Article.
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Background and Aims How plant cell-cycle genes interface with development is unclear. Preliminary evidence from our laboratory suggested that over-expression of the cell cycle checkpoint gene, WEE1, repressed growth and development. Here the hypothesis is tested that the level of WEE1 has a dosage effect on growth and development in Arabidospis thaliana. To do this, a comparison was made of the development of gain- and loss-of-function WEE1 arabidopsis lines both in vivo and in vitro.
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