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A Case series study on complications after breast augmentation with Macrolane™

Becchere, Maria Paola and Farace, Francesco and Dessena, Lidia and Marongiu, Francesco and Bulla, Antonio and Simbula, Luca and Meloni, Giovanni Battista and Rubino, Corrado (2013) A Case series study on complications after breast augmentation with Macrolane™. Aesthetic Plastic Surgery, Vol. 37 (2), p. 332-335. eISSN 1432-5241. Article.

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DOI: 10.1007/s00266-012-9971-5


Background The use of Macrolane™ seems to have several advantages compared to the other standard methods for breast augmentation: it is faster, less invasive, and requires only local anesthesia. Nevertheless, various complications associated with the use of Macrolane™ have been described, e.g., encapsulated lumps in breast tissue, infection, and parenchymal fibrosis. We report the results of our case series study on the clinical and imaging evaluations of patients who came to our attention after breast augmentation with Macrolane™ injection and evaluate the effect of this treatment on breast cancer screening procedures.
Methods Between September 2009 and July 2010, seven patients, treated elsewhere with intramammary Macrolane™ injection for cosmetic purposes, presented to our institution complaining of breast pain. In all patients, Macrolane™ had been injected under local anesthesia in the retromammary space through a surgical cannula.
Results On mammography, nodules appeared as gross lobulated radiopacities with polycyclic contours. On breast ultrasound, the nodules showed hypo-anaechogenic cystlike features. In all cases, image analysis by the radiologist was hindered by the presence of the implanted substance, which did not allow the complete inspection of the whole breast tissue.
Conclusions From our experience, although safe in other areas, injection of Macrolane™ into breast tissue cannot be recommended at this time. Our study, along with other reports, supports the need to start a clinical trial on the use of injectable fillers in the breast to validate their safety and effectiveness.

Item Type:Article
ID Code:8915
Uncontrolled Keywords:Mammary augmentation with NASHA, Macrolane™, mammography of augmented breast, breast augmentation
Subjects:Area 06 - Scienze mediche > MED/19 Chirurgia plastica
Area 06 - Scienze mediche > MED/36 Diagnostica per immagini e radioterapia
Divisions:001 Università di Sassari > 01-a Nuovi Dipartimenti dal 2012 > Scienze Chirurgiche, Microchirurgiche e Mediche
Copyright Holders:© Springer Science+Business Media, LLC and International Society of Aesthetic Plastic Surgery 2013
Deposited On:24 Apr 2013 12:20

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