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Nickel interaction with metal binding sequences of histone H4

Zoroddu, Maria Antonietta and Peana, Massimiliano Francesco and Medici, Serenella and Kowalik-Jankowska, Teresa and Kozlowski, Henryk and Costa, Max (2004) Nickel interaction with metal binding sequences of histone H4. In: ICCC36: 36. International conference on coordination chemistry, July 18-23, 2004, Mérida-Yucatán, México. Mérida, [s.n.]. p. 370. Conference or Workshop Item.

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Nickel compounds are well known as human carcinogens.
We investigated the issue of Ni(II) binding within the histone octamer. Using histone sequences in conjuction with the structural data we identified a binding site for Ni(II) ions located in the N-terminal tail of the histone H4.

Item Type:Conference or Workshop Item (Poster)
ID Code:8852
Uncontrolled Keywords:Histone H4, nickel compounds, carcinogenesis
Subjects:Area 03 - Scienze chimiche > CHIM/03 Chimica generale e inorganica
Divisions:001 Università di Sassari > 01 Dipartimenti > Chimica
Deposited On:22 Apr 2013 10:55

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