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Nickel interaction with metal binding sequences of histone H4

Zoroddu, Maria Antonietta and Peana, Massimiliano Francesco and Medici, Serenella and Kowalik-Jankowska, Teresa and Kozlowski, Henryk and Costa, Max (2004) Nickel interaction with metal binding sequences of histone H4. In: ICCC36: 36. International conference on coordination chemistry, July 18-23, 2004, Mérida-Yucatán, México. Mérida, [s.n.]. p. 370. Conference or Workshop Item.

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Abstract

Nickel compounds are well known as human carcinogens.
We investigated the issue of Ni(II) binding within the histone octamer. Using histone sequences in conjuction with the structural data we identified a binding site for Ni(II) ions located in the N-terminal tail of the histone H4.

Item Type:Conference or Workshop Item (Poster)
ID Code:8852
Status:Published
Uncontrolled Keywords:Histone H4, nickel compounds, carcinogenesis
Subjects:Area 03 - Scienze chimiche > CHIM/03 Chimica generale e inorganica
Divisions:001 Università di Sassari > 01 Dipartimenti > Chimica
Publisher:[s.n.]
Deposited On:22 Apr 2013 10:55

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