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Chemical composition and antimicrobial action of the essential oils of Salvia desoleana and S. sclarea

Peana, Alessandra Tiziana and Moretti, Mario Domenico Luigi and Juliano, Claudia Clelia Assunta (1999) Chemical composition and antimicrobial action of the essential oils of Salvia desoleana and S. sclarea. Planta Medica, Vol. 65 (8), p. 752-754. eISSN 1439-0221. Article.

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DOI: 10.1055/s-2006-960857


The chemical composition of the essential oils of Salvia desoleana Atzei & Picci and Salvia sclarea L. from Sardinia (Italy) was analysed by GC and CC/MS. S. desoleana oil had a high content of monoterpenic esters (linalyl acetate and alpha-terpinyl acetate) and a lower amount of the corresponding alcohols while S. sclarea oil was characterised by a higher content of alcohols and lower quantity of esters. We studied the antimicrobial activity of these oils concerning their use in pharmaceutical preparations for local application. Only weak microbiostatic inhibitory activity was seen against S. aureus, E. coli, S. epidermidis and C. albicans, but since inhibition increased progressively with contact time, better results could be obtained by using these oils in bioadhesive formulations that would also have anti-inflammatory and peripheral analgesic action at a local level, as demonstrated in experimental animals following systemic application.

Item Type:Article
ID Code:8818
Uncontrolled Keywords:Salvia desoleana, Salvia sclarea, chemical composition
Subjects:Area 05 - Scienze biologiche > BIO/14 Farmacologia
Area 03 - Scienze chimiche > CHIM/09 Farmaceutico tecnologico applicativo
Divisions:001 Università di Sassari > 01 Dipartimenti > Scienze del farmaco
Deposited On:25 Mar 2013 13:06

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