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Risk factors associated with Helicobacter pylori infection among children in a defined geographic area

Dore, Maria Pina and Malaty, Hoda M. and Graham, David Y. and Fanciulli, Giuseppe and Delitala, Giuseppe and Realdi, Giuseppe (2002) Risk factors associated with Helicobacter pylori infection among children in a defined geographic area. Clinical Infectious Diseases, Vol. 35 , p. 240-245. eISSN 1537-6591. Article.

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DOI: 10.1086/341415


Factors influencing the pattern of Helicobacter pylori infection among children living in adjacent urban and rural areas of northern Sardinia, Italy, were compared. The seroprevalence of H. pylori infection was 22% (625 of 2810 children) in the study population and was significantly higher among children in rural areas (37%) than in urban areas (13%) (odds ratio [OR], 3.8; 95% confidence interval [CI], 3.2–4.7; P <.005). This difference was consistent within each age group. In rural areas, children who had dogs were at greatest risk for H. pylori infection (OR, 1.8; 95% CI, 1.3–2.6; P <.05). No association was seen between H. pylori sero-positivity and a history of breast-feeding. Urban children attending day care centers had a higher prevalence of infection (17%) than did those who never attended (12%) (OR, 1.5; 95% CI, 1.1–2.0; P <.05). The epidemiology of H. pylori infection is complex; even within the same geographic area, different factors influence acquisition of H. pylori infection.

Item Type:Article
ID Code:873
Uncontrolled Keywords:H. pylori, rural vs urban areas, northern Sardinia
Subjects:Area 06 - Scienze mediche > MED/13 Endocrinologia
Area 06 - Scienze mediche > MED/12 Gastroenterologia
Area 06 - Scienze mediche > MED/09 Medicina interna
Divisions:001 Università di Sassari > 03 Istituti > Clinica medica generale e terapia medica
Publisher:University of Chicago Press
Copyright Holders:© 2002 by the Infectious Diseases Society of America
Publisher Policy:Depositato in conformità con la politica di copyright dell'Editore
Deposited On:18 Aug 2009 10:03

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