Evidente, Antonio and Cabras, Anna Lisa and Maddau, Lucia and Serra, Salvatorica and Andolfi, Anna and Motta, Andrea (2003) Viridepyronone, a new antifungal 6-substituted 2H-Pyran-2-one produced by Trichoderma viride. Journal of Agricultural and Food Chemistry, Vol. 51 (24), p. 6957-6960. eISSN 1520-5118. Article.
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A new antifungal 6-substituted 2H-pyran-2-one, named viridepyronone, has been isolated from a cultural filtrate of a strain of Trichoderma viride showing antagonistic activity in vitro toward Sclerotium rolfsii, which is the causal agent of crown and stem rot of artichoke. Viridepyronone was characterized as 6-(4-oxopentyl)-2H-pyran-2-one 2 with spectroscopic methods. Bioassays showed that viridepyronone had a good antifungal activity against S. rolfsii, and its minimum inhibitory concentration (over 90% inhibition) was found to be 196 μg/mL. This is the first report of viridepyronone produced by any species of fungi.
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