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Enzyme immunoassay for urogenital trichomoniasis as a marker of unsafe sexual behaviour

Mason, Peter R. and Gregson, Simon and Gwanzura, Lovemore and Cappuccinelli, Pietro Antonio and Rapelli, Paola and Fiori, Pier Luigi (2001) Enzyme immunoassay for urogenital trichomoniasis as a marker of unsafe sexual behaviour. Epidemiology and Infection, Vol. 126 (1), p. 103-109. eISSN 1469-4409. Article.

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Abstract

Enzyme immunoassay (EIA) was used to detect antibodies to Trichomonas vaginalis in sera from Zimbabwe. The EIA showed a sensitivity of 95 and 94% when compared with vaginal swab culture among women attending a family planning clinic (FPC) and female commercial sex workers (CSW) respectively. The specificity was 85 and 77% in the two groups. Culturenegative FPC women were sub-divided into high risk or low risk of exposure to trichomoniasis. The seroprevalence was 10% (6/61) among low risk women, 21% (10/48) among high risk women and 23% (9/39) among culture negative CSW. The EIA was positive in 46% (18/39) men with genital discharge but only 5% (2}37) healthy blood donors. None of 31 sera from prepubescent children was positive. The EIA may be useful for community surveys of trichomoniasis. Because T. vaginalis is a common sexually transmitted disease, the test may indicate behaviour that increases the risk of STD transmission.

Item Type:Article
ID Code:813
Status:Published
Refereed:Yes
Uncontrolled Keywords:Infection, parasitosis, protozoal disease, transmitted disease, trichomoniasis, enzyme immunoassay (EIA), Trichomonas vaginalis, Africa, Zimbabwe
Subjects:Area 06 - Scienze mediche > MED/07 Microbiologia e microbiologia clinica
Divisions:001 Università di Sassari > 01 Dipartimenti > Scienze biomediche
Publisher:Cambridge University Press
eISSN:1469-4409
Publisher Policy:Depositato in conformità con la politica di copyright dell'Editore
Deposited On:18 Aug 2009 10:03

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