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Porcheddu, Andrea and De Luca, Lidia Vera Giovanna (2012) Iron-catalyzed amidation of aldehydes with N-chloroamines. Advanced Synthesis & Catalysis, Vol. 354 (16), p. 2949-2953. eISSN 1615-4169. Article. Full text not available from this repository. AbstractA new direct conversion of aldehydes to amides has been realized, in the presence of iron(III) chloride as a catalyst and using tert-butyl hydroperoxide (TBHP) as an oxidant. Both aliphatic and aromatic aldehydes were successfully reacted with variously mono- and di-substituted N-chloroamines. The methodology has a wide substrate scope, uses cheap and easily available reagents and is characterized by short reaction times.
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