Zinellu, Angelo and Sotgia, Salvatore and Scanu, Bastianina and Deiana, Luca and Talanas, Giuseppe and Terrosu, Pier Franco and Carru, Ciriaco (2012) Low density lipoprotein S-homocysteinylation is increased in acute myocardial infarction patients. Clinical Biochemistry, Vol. 45 (4-5), p. 359-362. ISSN 0009-9120. Article.
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We have investigated on the levels of homocysteine linked to LDL in acute myocardial infarction patients.
Design and methods
We used capillary electrophoresis to measure LDL-bound thiols in 16 AMI individuals and 32 healthy volunteers.
We found a significant increase of apo-B homocysteine and cysteine levels in LDL fraction of AMI subjects.
Our findings suggest that also LDL S-homocysteinylation may be considered among the markers for the CVD risk evaluation.
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