Migliori, Giovanni Battista and Sotgiu, Giovanni (2012) Treatment of tuberculosis: have we turned the corner? The Lancet, Vol. 380 (9846), p. 955-957. eISSN 1474-547X. Article.
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The number of multidrug-resistant (MDR) tuberculosis cases officially reported to WHO increased from 29 000 to 53 000 between 2008 and 2010, still representing only 18% of the estimated 290 000 patients potentially identifiable if drug susceptibility testing was done in all notified cases of tuberculosis. A recent study done in Belarus showed a new global record for prevalence of MDR tuberculosis with 35·3% of new patients and 76·5% of previously treated patients diagnosed with the disease. This finding clearly shows how far case mismanagement can affect the chances to control (and eventually eliminate) the disease.
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