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Immunofluorescence of the tubulin system in human skin fibroblasts in Werner's syndrome, Kaposi sarcoma, and psoriasis

Rubino, Salvatore and Fiori, Pier Luigi and Lubinu, Giuseppe and Scappaticci, S. and Cerimele, Decio (1981) Immunofluorescence of the tubulin system in human skin fibroblasts in Werner's syndrome, Kaposi sarcoma, and psoriasis. Archives of dermatological research, Vol. 272 (1-2), p. 143-145. eISSN 1432-069X. Article.

Full text not available from this repository.

DOI: 10.1007/BF00510405

Abstract

Reduced survival of skin fibroblasts in cell cultures and laterations of fibroblast gene products, such as surface antigens HLA2 and HLA9 and a cytoplasmic enzyme, glucose-6-phosphate dehydrogenase, have been recently demonstrated in a patient affected by Werner's syndrome. In order to investigate the morphology of the fibroblasts from patients affected by Werner's syndrome it was decided to study the tubulin system in primary cell cultures. Microtubules are tubular structures, 20-25 nm wide, and are thought to play a significant role in cell morphology and in the regulation of intracellular movements. Fibroblast cultures from normal subjects and from patients affected by Kaposi's sarcoma and by psoriasis were studied as controls.

Item Type:Article
ID Code:7790
Status:Published
Refereed:Yes
Subjects:Area 03 - Scienze chimiche > CHIM/03 Chimica generale e inorganica
Area 06 - Scienze mediche > MED/07 Microbiologia e microbiologia clinica
Divisions:001 Università di Sassari > 01 Dipartimenti > Scienze biomediche
001 Università di Sassari > 01 Dipartimenti > Chimica
Publisher:Springer
eISSN:1432-069X
Additional Information:A. di pubblicazione nel documento 1982.
Deposited On:17 Jul 2012 14:01

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