UnissResearch

Logo Universitàegli studi di Sassari
titoli, abstracts, parole chiave >>>
Genetic variation within and between G1 and G3 genotypes of Echinococcus granulosus in Italy revealed by multilocus DNA sequencing

Busi, Marina and Šnábel, Viliam and Varcasia, Antonio and Garippa, Giovanni and Perrone, Vitantonio and De Liberato, Claudio and D'Amelio, Stefano (2007) Genetic variation within and between G1 and G3 genotypes of Echinococcus granulosus in Italy revealed by multilocus DNA sequencing. Veterinary Parasitology, Vol. 150 (1-2), p. 75-83. eISSN 1873-2550. Article.

Full text not available from this repository.

DOI: 10.1016/j.vetpar.2007.09.003

Abstract

Numerous studies have provided evidence that Echinococcus granulosus exists as a complex of different strains, that differ in a wide variety of criteria that have an impact on the epidemiology, pathology and control of cystic hydatid disease (CHD) and, to date, 10 distinct genotypes (G1–G10) have been identified. In Italy, sequence analysis of the mitochondrial cox1 and nad1 genes showed the occurrence of the G1 genotype, the common sheep strain, the G3 genotype, the buffalo strain and of one isolate identified as G2 genotype, the Tasmanian sheep strain. In the present work, we have analysed E. granulosus strains in Italy, by genotyping a large sample of isolates and by checking out the genetic differentiation within and among the G1 and G3 genotypes using an additional mitochondrial gene as marker, the rrnS gene. Sequencing of the rrnS gene revealed a significant genetic differentiation between isolates identified as belonging to the G1 and G3 genotypes, with fixed nucleotide substitutions. This study provides further evidence of the occurrence of the E. granulosus G3 buffalo strain in Italy, a strain previously thought to be confined to the Indian region.

Item Type:Article
ID Code:7776
Status:Published
Refereed:Yes
Uncontrolled Keywords:Echinococcus granulosus, genotypes, Mitochondrial DNA genes, Italy
Subjects:Area 07 - Scienze agrarie e veterinarie > VET/06 Parassitologia e malattie parassitarie degli animali
Divisions:001 Università di Sassari > 01 Dipartimenti > Biologia animale
Publisher:Elsevier
eISSN:1873-2550
Deposited On:13 Jul 2012 11:29

I documenti depositati in UnissResearch sono protetti dalle leggi che regolano il diritto d'autore

Repository Staff Only: item control page