Perán, Macarena and García, María Angel and López-Ruiz, Elena and Bustamante, Milán and Jiménez, Gema and Madeddu, Roberto Beniamino and Marchal Corrales, Juan Antonio (2012) Functionalized nanostructures with application in regenerative medicine. International Journal of Molecular Sciences, Vol. 13 (3), p. 3847-3886. eISSN 1422-0067. Article.
In the last decade, both regenerative medicine and nanotechnology have been broadly developed leading important advances in biomedical research as well as in clinical practice. The manipulation on the molecular level and the use of several functionalized nanoscaled materials has application in various fields of regenerative medicine including tissue engineering, cell therapy, diagnosis and drug and gene delivery. The themes covered in this review include nanoparticle systems for tracking transplanted stem cells, self-assembling peptides, nanoparticles for gene delivery into stem cells and biomimetic scaffolds useful for 2D and 3D tissue cell cultures, transplantation and clinical application.
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