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Epidemiology, virulence factors and antibiotic resistance in Staphylococcus aureus strains isolated in small ruminant dairy chain

Spanu, Vincenzo (2012) Epidemiology, virulence factors and antibiotic resistance in Staphylococcus aureus strains isolated in small ruminant dairy chain. Doctoral Thesis.

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Abstract

The aim of the present thesis was to conduct an extensive characterization of S. aureus isolated from small ruminant milk and dairy products. S. aureus is considered a major public health concern because of its ability to give disease in human, after consumption of contaminated foods with enterotoxins. This pathogen can aquire resistance against several antibiotics used in human and veterinary practices. Farms and cheese-making plants can serve as a reservoir of S. aureus and are involved in the spread of the microorganism into environment. Concern exists on the possible acquisition of antibiotic resistance by human strains, as consequence of exchange of mobile genetic elements with strains of animal origin. The extent and impact of these strains on human health was also assessed.
In chapters 3, 4, and 5 are presented results on prevalence, virulence factors and antibiotic resitance of S. aureus strains isolated from goats with subclinical mastitis and from bulk tank milk. In chapters 6, 7 and 8 are reported results on S. aureus strains isolated from raw sheep’s milk cheese. Prevalence, virulence daterminants and antibiotic resistance have been assessed. Additional informations have been provided on the genetic variability of the strains and their relationship with the host.

Item Type:Doctoral Thesis
ID Code:6780
Contributors:Scarano, Christian
Publisher:Università degli studi di Sassari
Uncontrolled Keywords:Staphylococcus aureus, small ruminant dairy chain, antibiotic resistance, virulence factors, genetic variability
Subjects:Area 07 - Scienze agrarie e veterinarie > VET/04 Ispezione degli alimenti di origine animale
Divisions:001 Università di Sassari > 01 Dipartimenti > Biologia animale
Cicli, scuole e corsi:Ciclo 24 > Scuole > Riproduzione, produzione, benessere animale e sicurezza degli alimenti di origine animale > Produzione e sicurezza degli alimenti di origine animale
Deposited On:27 Mar 2012 09:21

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