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Synthesis and D2-like binding affinity of new derivatives of N3-[(1- ethyltetrahydro-1H-2-pyrrolyl)methyl]-4,5-dihydrobenzo[g]indole-3- carboxamide and related compounds

Pinna, Gérard Aimé and Pirisi, Maria Antonietta and Chelucci, Giorgio Adolfo and Mussinu, Jean-Mario and Murineddu, Gabriele and Maciocco, Elisabetta (2000) Synthesis and D2-like binding affinity of new derivatives of N3-[(1- ethyltetrahydro-1H-2-pyrrolyl)methyl]-4,5-dihydrobenzo[g]indole-3- carboxamide and related compounds. In: SardiniaChem 2000: giornata di studio dedicata alla chimica organica delle molecole biologicamente attive, 22 Maggio 2000, Porto Conte, Alghero, Italia. Conference or Workshop Item.

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Abstract

In previous papers 4a,b we have reported the syntheses and structure-activity relationships of a series of 5-phenyl-3-pyrrole carboxamide and related 4,5-dihydrobenzo[g]indole-3-carboxamide analogues whose most representative terms were 1a and 2a respectively. Encouraged by these results we carried out several modifications of 2a.

Item Type:Conference or Workshop Item (Poster)
ID Code:677
Status:Published
Uncontrolled Keywords:Dopamine receptors, antipsychotics
Subjects:Area 03 - Scienze chimiche > CHIM/06 Chimica organica
Area 03 - Scienze chimiche > CHIM/08 Chimica farmaceutica
Divisions:001 Università di Sassari > 01 Dipartimenti > Chimica
001 Università di Sassari > 01 Dipartimenti > Farmaco, chimico, tossicologico
Additional Information:Comitato organizzatore di SardiniaChem 2000: Salvatore Cabiddu, Pier Paolo Piras Università di Cagliari, Giovanna Delogu CNR Sassari, Maurizio Taddei Università di Sassari.
Deposited On:18 Aug 2009 10:02

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