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Chromophore-modified bis-benzo[g]indolecarboxamides: synthesis and citotoxicity of bis-benzo[g]indazole-3-carboxamides and related compounds

Pinna, Gérard Aimé and Pirisi, Maria Antonietta and Murineddu, Gabriele and Mussinu, Jean-Mario and Grella, Giuseppe Enrico (2000) Chromophore-modified bis-benzo[g]indolecarboxamides: synthesis and citotoxicity of bis-benzo[g]indazole-3-carboxamides and related compounds. In: SardiniaChem 2000: giornata di studio dedicata alla chimica organica delle molecole biologicamente attive, 22 Maggio 2000, Porto Conte, Alghero, Italia. Conference or Workshop Item.

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Abstract

Cancer chemoteraphy continue to be an important research avenue. Combination chemotherapy using antineoplastic agents with different mechanisms of action is one method employed to combat this disease. Thus, a single molecule containing two functional groups, each with a different mechanism of action, also could prove beneficial in cancer treatment. Syntheses and biological results are reported.

Item Type:Conference or Workshop Item (Poster)
ID Code:675
Status:Published
Uncontrolled Keywords:Cancer chemoteraphy, antineoplastic agents, bis-benzo[g]indolecarboxamides, bis-benzo[g]indazole-3-carboxamides
Subjects:Area 03 - Scienze chimiche > CHIM/08 Chimica farmaceutica
Divisions:001 Università di Sassari > 01 Dipartimenti > Farmaco, chimico, tossicologico
Additional Information:Comitato organizzatore di SardiniaChem 2000: Salvatore Cabiddu, Pier Paolo Piras Università di Cagliari, Giovanna Delogu CNR Sassari, Maurizio Taddei Università di Sassari.
Deposited On:18 Aug 2009 10:02

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