A Systematic review of microsurgical reconstruction of the jaws using vascularized fibula flap technique in patients with bisphosphonate-related osteonecrosis

Sacco, Roberto and Sacco, Gianluca and Acocella, Alessandro and Sale, Silvana and Sacco, Nicola and Baldoni, Edoardo (2011) A Systematic review of microsurgical reconstruction of the jaws using vascularized fibula flap technique in patients with bisphosphonate-related osteonecrosis. Journal of Applied Oral Science, Vol. 19 (4), p. 293-300. eISSN 1678-7765. Article.

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Abstract

OBJECTIVE: The aim of this systematic review was to assess the role of microsurgical reconstruction of the jaws in patients with bisphosphonate-related osteonecrosis, and biological complications after an observation period of at least 12 months. Material and methods: An electronic MEDLINE search supplemented by manual searching was conducted to identify studies reporting data of at least 12 months observation on the microsurgical reconstruction of the jaws in patients with bisphosphonate-related osteonecrosis.
RESULTS: Four studies resulted eligible for the analysis yielded. Three out of five studies were free of complications, with a success rate of 100% as no recurrence of osteonecrosis was registered.

CONCLUSIONS: Microsurgical reconstruction of the jaws represents a valid treatment modality in patients with bisphosphonate-related osteonecrosis at 3^rd stage of the disease.

Item Type:	Article
ID Code:	6571
Status:	Published
Refereed:	Yes
Uncontrolled Keywords:	Jaw diseases, osteonecrosis, bisphosphonates
Subjects:	Area 06 - Scienze mediche > MED/28 Malattie odontostomatologiche
Divisions:	001 Università di Sassari > 01 Dipartimenti > Chirurgia, microchirurgia e specialità medico-chirurgiche
Publisher:	Universidade de Sao Paulo / Faculdade de Odontologia de Bauru
eISSN:	1678-7765
Deposited On:	16 Nov 2011 12:52

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