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Emerging epidemic of drug-resistant tuberculosis in Europe, Russia, China, South America and Asia: current status and global perspectives

Migliori, Giovanni Battista and Centis, Rosella and Lange, Christoph and Richardson, Morgan D’Arcy and Sotgiu, Giovanni (2010) Emerging epidemic of drug-resistant tuberculosis in Europe, Russia, China, South America and Asia: current status and global perspectives. Current Opinion in Pulmonary Medicine, Vol. 16 (3), p. 171-179. ISSN 1070-5287. Article.

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DOI: 10.1097/MCP.0b013e328337573e

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Purpose of review:
Drug resistance, particularly through multidrug-resistant tuberculosis (TB) and extensively drug-resistant TB strains, poses a real threat to TB control worldwide. Recent reports from the WHO and the International Union Against Tuberculosis and Lung Disease demonstrate that the emerging epidemic of drug-resistant TB is a global problem, although emphasis has been placed on several 'hot spots' because of lack of good global data.
Recent findings:
The present article is aimed at reviewing the available information on drug-resistant TB with special focus on the features of the epidemic in Europe, Russia, Latin America, Asia and specifically China, and to discuss the global perspectives related to drug-resistant TB control and care.
Drug-resistant TB originates from different human errors, including misuse of anti-TB drugs and other reasons related to prescribers, patients and drug producers. Although there is an urgent need for new drugs, a sound public health approach is necessary for their introduction in clinical treatment settings to prevent/avoid creating additional resistance, as has already been observed for first and second-line anti-TB drugs in many settings.

Item Type:Article
ID Code:6424
Uncontrolled Keywords:Asia, China, drug-resistant tuberculosis, Europe, extensively drug-resistant tuberculosis, Latin America, multidrug-resistant tuberculosis, Russia, tuberculosis
Subjects:Area 06 - Scienze mediche > MED/01 Statistica medica
Divisions:001 Università di Sassari > 03 Istituti > Igiene e medicina preventiva
Publisher:Lippincott Williams & Wilkins
Copyright Holders:© 2010 Wolters Kluwer Health | Lippincott Williams & Wilkins
Deposited On:30 Aug 2011 11:14

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