Phylogenetic analysis of small ruminant lentivirus (SRLV) in Italian flocks reveals the existence of novel genetic subtypes

Giammarioli, Monica and Bazzucchi, Moira and Puggioni , Giantonella and Brajon, Giovanni and Dei Giudici, Silvia and Taccori, Flavia and Feliziani, Francesco and De Mia, Gian Mario (2011) Phylogenetic analysis of small ruminant lentivirus (SRLV) in Italian flocks reveals the existence of novel genetic subtypes. Virus Genes, Vol. 43 (3), p. 380-384. ISSN 0920-8569. eISSN 1572-994X. Article.

Full text not available from this repository.

DOI: 10.1007/s11262-011-0653-1

Abstract

In order to investigate the genetic heterogeneity of small ruminant lentivirus (SRLV) isolates in Italy, 55 clinical samples collected between 1998 and 2010 were analysed. The phylogenetic study was based on analysis of gag–pol sequences. Our findings revealed that the SRLVs belonged to the subtype A9 (n = 3, sheep), B1 (n = 5, goat), B2 (n = 3, sheep) and E2 (n = 5, goat). Interestingly, 39 isolates from both sheep and goat, significantly differed from all the other SRLVs previously described and formed two separate clusters within genotypes A and B tentatively named A11 (n = 27, goat and sheep) and B3 (n = 12, goat and sheep), which have never been shown before. These results revealed a marked diversity among Italian field SRLV strains which might reflect the absence of any systematic control measures.

Item Type:	Article
ID Code:	6396
Status:	Published
Refereed:	Yes
Uncontrolled Keywords:	SRLV, gag–pol gene, phylogenetic analysis
Subjects:	Area 07 - Scienze agrarie e veterinarie > VET/06 Parassitologia e malattie parassitarie degli animali
Divisions:	002 Altri enti e centri di ricerca del Nord Sardegna > Istituto zooprofilattico sperimentale della Sardegna, Sassari
Publisher:	Springer Netherlands
ISSN:	0920-8569
eISSN:	1572-994X
Copyright Holders:	© Springer Science+Business Media, LLC 2011
Additional Information:	The online version of this article contains supplementary material, which is available to authorized users.
Deposited On:	24 Aug 2011 10:11

I documenti depositati in UnissResearch sono protetti dalle leggi che regolano il diritto d'autore

Repository Staff Only: item control page