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Special issue on “molecular mechanisms and new therapeutic targets in human carcinogenesis”

Feo, Francesco and Poli, Giuseppe (2010) Special issue on “molecular mechanisms and new therapeutic targets in human carcinogenesis”. Molecular Aspects of Medicine, Vol. 31 (2), p. 133-134. eISSN 1872-9452. Article.

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DOI: 10.1016/j.mam.2010.02.002


This special issue of the Journal of Molecular Aspects of Medicine has not been conceived to propose a comprehensive overview of all recent advances in the personalized molecular therapy of tumor. The aim of this issue is to focus on some of the major topics, treated by experts in the field, devoted to looking to the future of cancer therapy. The lesson for future developments is the need to expand our knowledge on the dysregulation of cellular signal transduction mechanisms, involved in cancer development and progression, in order to identify novel “druggable” targets and treatments based on patients’ particular genetic signatures. Moreover, the effects of the combined inhibition of different pathways, the correlations between molecular dysregulation and clinical response to therapy, and the methods to select the patients which could take advantage from a personalized molecular therapy are major themes treated in the present special issue, which can hopefully provide stimulus for further advances in the field.

Item Type:Article
ID Code:5647
Uncontrolled Keywords:Molecular therapy, human carcinogenesis
Subjects:Area 06 - Scienze mediche > MED/04 Patologia generale
Divisions:001 Università di Sassari > 01 Dipartimenti > Scienze biomediche
Publisher:Pergamon / Elsevier
Copyright Holders:© 2010 Elsevier
Deposited On:09 Mar 2011 09:30

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