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Hyperbaric oxygen and nadroparin calcium in the therapy of combined branch retinal artery and central retinal vein occlusion

Pinna, Antonio <1963- > and Fimiani, F. and Tendas, D. and Bolognini, Alfonso and Carta, Francesco (2010) Hyperbaric oxygen and nadroparin calcium in the therapy of combined branch retinal artery and central retinal vein occlusion. Acta Ophthalmologica, Vol. 88 (Suppl. 246). eISSN 1755-3768. Article.

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DOI: 10.1111/j.1755-3768.2010.267.x


Purpose. Branch retinal artery obstruction with simultaneous central retinal vein occlusion (BRAO/CRVO) is a rare condition. We describe 3 cases of BRAO/CRVO successfully treated with hyperbaric oxygen (HBO) and subcutaneous nadroparin calcium.
Methods. The first patient, a 42-year-old man, developed sudden visual loss (hand-motion) in his left eye one day after tonsillectomy. The second patient, a 60-year-old man with hypercholesterolemia, complained of sudden visual loss (finger counting) in his left eye upon arising. The third patient, an apparently healthy 39-year-old bricklayer, noted an acute decrease in his left vision (20/70) while working. In all patients, fundus evaluation and fluorescein angiography revealed BRAO/CRVO.
Results. All patients were treated with HBO at 2.5 atmospheres (15-20 sessions) and subcutaneous nadroparin calcium (200 UI/Kg/die) for 6 weeks. Two months later, there was complete resolution of the clinical signs of BRAO/CRVO and left visual acuity was 20/25 in patient 1, 20/32 in patient 2, and 20/20 in patient 3. Patient 2 had an improvement in the left visual field, but there was still a discrete cecocentral scotoma.
Conclusion. In these 3 patients with BRAO/CRVO, vision returned to near normal after prompt treatment with HBO and subcutaneous nadroparin calcium. We have to acknowledge that the effect of our intervention cannot be determined from 3 cases and no control. Nevertheless, a comparison between our results and those reported in similar cases seem to suggest that this therapy may be beneficial in the management of BRAO/CRVO.

Item Type:Article
ID Code:5471
Uncontrolled Keywords:Branch retinal artery obstruction (BRAO), Central retinal vein occlusion (BRAO/CRVO), treatment, hyperbaric oxygen (HBO)
Subjects:Area 06 - Scienze mediche > MED/30 Malattie apparato visivo
Divisions:001 Università di Sassari > 03 Istituti > Oftalmologia, Otorinolaringoiatria e Urologia
002 Altri enti e centri di ricerca del Nord Sardegna > Centro iperbarico sassarese, Sassari
Publisher:Blackwell / Wiley
Additional Information:Abstract n. 267 presented at the European Association for Vision and Eye Research Conference, Crete (Greece) 6-9 October 2010.
Deposited On:28 Mar 2011 12:47

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