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Pathogenetic investigations on the enteric nervous system plexuses of sarda breed sheep with different PrP genotypes following oral experimental scrapie infection

Marruchella, Giuseppe and Malatesta, Daniela and Petrucci, Luigi and Lalatta-Costerbosa, Giovanna and Clavenzani, Paolo and Chiocchetti, Roberto and Mazzoni, Maurizio and Albanese, Valeria and Agrimi, Umberto and D'Agostino, Claudia and Vaccari, Gabriele and Nonno, Romolo and De Grossi, Luigi and Rosone, Francesca and Giordani, Francesco and Ligios, Ciriaco and Sarli, Giuseppe and Di Guardo, Giovanni (2006) Pathogenetic investigations on the enteric nervous system plexuses of sarda breed sheep with different PrP genotypes following oral experimental scrapie infection. In: 3. Congresso nazionale A.I.P.Vet.: atti, 11-13 Maggio 2006, Pisa, Italia. Milano, AIPVet. p. 26-27. ISSN 1825-2265. Conference or Workshop Item.

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Abstract

We investigated the ileal myenteric (MPs) and submucosal plexuses (SMPs) of 32 Sarda breed sheep carrying different PrP genotypes (ARQ/ARQ, ARQ/AHQ, ARQ/ARR, ARR/ARR), which had been orally dosed with scrapie at 8 months of age and euthanized at definite time intervals post-infection (p.i.).

Item Type:Conference or Workshop Item (Lecture)
ID Code:531
Status:Published
Uncontrolled Keywords:Experimental scrapie, enteric nervous system, sheep
Subjects:Area 07 - Scienze agrarie e veterinarie > VET/03 Patologia generale e anatomia patologica veterinaria
Divisions:002 Altri enti e centri di ricerca del Nord Sardegna > Istituto zooprofilattico sperimentale della Sardegna, Sassari
Publisher:AIPVet
ISSN:1825-2265
Deposited On:18 Aug 2009 10:02

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