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The Influence of human maxillary sinus mucosa on maxillary bone resorption during pneumatisation proces

Wojtowicz, Andrzej and Sporniak-Tutak, Katarzyna and Montella, Andrea Costantino Mario and Bandiera, Pasquale and Dijakiewicz, Maciej and Kochanowska, Iwona and Ostrowski, Kazimierz (2005) The Influence of human maxillary sinus mucosa on maxillary bone resorption during pneumatisation proces. Durham Anthropology Journal, Vol. 12 (2-3). ISSN 1742-2930. Article.

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The aim of this study was an immunohistological investigation of the TGFß (transforming growth factor), BMP6 (bone morphogenetic protein), MMPs 1-3 (metalloproteinases) and TIMP-1 (tissue inhibitors of metalloproteinases) in the following tissue compartments: maxillary sinus epithelium-mucosa - maxillary bone - oral mucosa as well as a radiometric assessment of the anterior and posterior segments of maxillary bone. We were able to confirm the involvement of epithelium- mucosa in the growth and formation of maxillary sinuses and their pneumatisation in physiological conditions as well as in chronic allergic sinusitis. This is connected with the intense synthesis of MMP proteases, which, like in bones, regulates the turnover and rebuilding process of surrounding soft tissues. This is true for the control samples as well as for the samples taken from the cases of allergic maxillary sinusitis during surgery.

Item Type:Article
ID Code:530
Uncontrolled Keywords:Maxillary sinus, BMPs, TGFß, MMPs, TIMP, radiometry, embryogenesis, chronic allergic sinusitis
Subjects:Area 05 - Scienze biologiche > BIO/16 Anatomia umana
Divisions:001 Università di Sassari > 01 Dipartimenti > Scienze biomediche
Publisher:University of Durham, Department of Anthropology
Copyright Holders:© 2005, Andrzej Wojtowicz, Katarzyna Sporniak-Tutak, Andrea Montella, Pasquale Bandiera, Maciej Dijakiewicz, Iwona Kochanowska and Kazimierz Ostrowski
Deposited On:18 Aug 2009 10:02

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