Cerri, Riccardo and Boatto, Gianpiero and Pau, Amedeo and Sparatore, Fabio and Cima, Lorenzo and Carrara, Maria and Satta, Margherita (1991) Formamidines with antinociceptive and antiinflammatory activities. Il Farmaco, Vol. 46 (2), p. 369-378. ISSN 0014-827X. Article.
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Pursuing our investigations on 7-amino-2,3-polymethyleneindole derivatives, a set of 7-(dimethylaminomethylene)-amino-2,3-polymethyleneindoles, together with some other aryl or cycloalkyl substituted formamidines, were prepared and tested for analgesic and antiinflammatory activities. Several compounds resulted endowed with one or both of these activities; the indole derivatives 1 and 2 exhibited a good degree of both of them.
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