Pau, Amedeo and Boatto, Gianpiero and Cerri, Riccardo and Palomba, Michele Francesco Luigi and Nicolai, Marco and Sparatore, Fabio and Varoni, Maria Vittoria (1993) Amides and formamidines with antinociceptive activity: note II. Il Farmaco, Vol. 48 (9), p. 1291-1299. ISSN 0014-827X. Article.
Forty amides, formamidines and trifluoromethylsulfonylamides bearing on the nitrogen a cyclohexyl residue, eventually 2-substituted, were prepared and tested for analgesic activity against a chemical stimulus. Good activity was exhibited by amides 9, 11 and 28, by formamidine 34, as well as by triflyamide 40. Eleven additional compounds exhibited a moderate activity.
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