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Synthesis of N-[4-(alkyl)cyclohexyl]-substituted benzamides with anti-inflammatory and analgesic activities

Pau, Amedeo and Boatto, Gianpiero and Palomba, Michele Francesco Luigi and Asproni, Battistina and Cerri, Riccardo and Palagiano, Francesco and Filippelli, Walter and Falcone, Giuseppe and Motola, Giulia (1999) Synthesis of N-[4-(alkyl)cyclohexyl]-substituted benzamides with anti-inflammatory and analgesic activities. Il Farmaco, Vol. 54 (8), p. 524-532. ISSN 0014-827X. Article.

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DOI: 10.1016/S0014-827X(99)00057-9

Abstract

Two series of N-[4-(alkyl)cyclohexyl]-substituted benzamides, i.e. a series of N-[4-(tert-butyl)cyclohexyl]-substituted benzamides and a series of N-[4-(ethyl)cyclohexyl]-substituted benzamides, were synthesised and evaluated for their anti-inflammatory and analgesic potencies, and gastrointestinal irritation liability.

Item Type:Article
ID Code:5269
Status:Published
Refereed:Yes
Uncontrolled Keywords:N-[4-(Alkyl)cyclohexyl]-substituted benzamides, anti-inflammatory agents, analgesic agents
Subjects:Area 03 - Scienze chimiche > CHIM/08 Chimica farmaceutica
Divisions:001 Università di Sassari > 01 Dipartimenti > Farmaco, chimico, tossicologico
Publisher:Elsevier
ISSN:0014-827X
Copyright Holders:© 1999 Elsevier Science
Deposited On:20 Dec 2010 18:40

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