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Detection of Mycobacterium avium subsp. paratuberculosis (MAP)-specific IS900 DNA and antibodies against MAP peptides and lysate in the blood of Crohn's disease patients

Di Sabatino, Antonio and Paccagnini, Daniela and Vidali, Francesca and Rosu, Valentina and Biancheri, Paolo and Cossu, Andrea and Zanetti, Stefania Anna Lucia and Corazza, Gino R. and Sechi, Leonardo Antonio (2011) Detection of Mycobacterium avium subsp. paratuberculosis (MAP)-specific IS900 DNA and antibodies against MAP peptides and lysate in the blood of Crohn's disease patients. Inflammatory Bowel Diseases, Vol. 17 (5), p. 1254-1255. eISSN 1536-4844. Article.

Full text not available from this repository.

DOI: 10.1002/ibd.21461

Abstract

Crohn's disease (CD) is a relapsing transmural chronic inflammatory bowel disease (IBD). Its etiology remains uncertain, and infectious causes have been proposed as an integral part of this process together with genetic and environmental factors. Mycobacterium avium subspecies paratuberculosis (MAP), an acid-fast bacillus causing a chronic granulomatous enteritis (Johne's disease) in ruminants, has been implicated in the pathogenesis of CD, although critics of the mycobacterial theory argue that MAP is a secondary invader rather than a causal factor.

Item Type:Article
ID Code:5163
Status:Published
Refereed:Yes
Uncontrolled Keywords:Crohn's disease (CD), Mycobacterium avium subsp. paratuberculosis, ulcerative colitis
Subjects:Area 06 - Scienze mediche > MED/07 Microbiologia e microbiologia clinica
Divisions:001 Università di Sassari > 01 Dipartimenti > Scienze biomediche
Publisher:Wiley
eISSN:1536-4844
Copyright Holders:© 2010 Crohn’s & Colitis Foundation of America
Deposited On:02 Dec 2010 13:36

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