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Vertebral augmentation with nitinol endoprosthesis: clinical experience with one year follow up in 40 patients

Manca, Antonio (2011) Vertebral augmentation with nitinol endoprosthesis: clinical experience with one year follow up in 40 patients. Doctoral Thesis.

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Aim: To assess safety, effectiveness and vertebral height restoration of prosthesis-assisted vertebroplasty during 1-year follow-up. Methods: 40 patients (36 females, mean age 73.6 years) were treated with percutaneous vertebral augmentation (PVA) performed by placement of nitinol implants. Fracture edema at MRI was required. All PVA were performed in local anesthesia with fluoroscopic-CT guidance. Implants were inserted through a bipedicular access. CT scan was performed to measure vertebral height (6 point) at baseline after the expanded implant was cemented and at 1-year follow up (f/u). Visual Analogue Scale (VAS) and Oswestry disability Index (ODI) were calculated before, after procedure. and at 1-year f/u (Mean:15 months). Results: No major complications occurred. 2 patients were lost at f/u. VAS and ODI were improved in 39 patients (97.5%) (p<0.0001 Wilcoxon test). Higher restoration values were in center measurement both in mid-coronal (3.9 mm, 3.0 SD) and in mid-sagittal reconstruction (4.7 mm, 3.6 SD). No significant height loss occurred over time. During follow-up no device change or migration was observed. 4 patients (10%) had a spontaneous new vertebral fracture. Conclusions: Vertebral augmentation performed with nitinol endoprosthesis is a safe and effective procedure. PVA provides a long-lasting pain relief and vertebral height gain.

Item Type:Doctoral Thesis
ID Code:5155
Contributors:Montella, Andrea Costantino Mario
Publisher:Universita' degli studi di Sassari
Uncontrolled Keywords:Vertebroplastica, vertebroplasty, vertebral augmentation, osteoporosi, osteoporosis
Subjects:Area 06 - Scienze mediche > MED/37 Neuroradiologia
Area 06 - Scienze mediche > MED/33 Malattie apparato locomotore
Area 06 - Scienze mediche > MED/36 Diagnostica per immagini e radioterapia
Area 05 - Scienze biologiche > BIO/16 Anatomia umana
Divisions:001 Università di Sassari > 01 Dipartimenti > Scienze biomediche
Cicli, scuole e corsi:Ciclo 23 > Scuole > Scienze biomediche > Fisiologia, farmacologia, morfologia e fisiopatologia del sistema nervoso
Deposited On:06 Apr 2011 12:11

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