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Clinical and cytogenetic studies in intersex ewes

Santucciu, Cinzia and Iannuzzi, Leopoldo and Fogu, Giuseppa and Bonelli, Piero and Bogliolo, Luisa and Rosati, Irma and Ledda, Sergio and Zedda, Maria Teresa and Pau, Salvatore (2006) Clinical and cytogenetic studies in intersex ewes. Caryologia, Vol. 59 (1), p. 67-74. ISSN 0008-7114. Article.

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Nine Sarda x Lacaune ewes with intersexual characteristics and an infertility condition at the reproductive anamnesis were analysed. In order to make a diagnosis, we have evaluated their behaviour and performed clinical and laparoscopic examination of the reproductive tract, as well as cytogenetic analysis. The ewes showed basically a female phenotype but a clinical examination revealed a different degree of masculinization in the morphology of external genital organs. A shorter vagina was observed in female-like ewes and a hypertrophic clitoris in male-like ewes. Laparoscopic analysis evidenced the presence of testis in seven individuals and, for two of them, the gonadal position was subcutaneous. Different male characteristics in the nine subjects, were also observed in their behaviour with a different degree of masculinization. Their blood samples were used for determining the percentage of male cells on lymphocytes chromosome spreads by using the C-banding technique. The haematopoietic chimeras (XX/ XY) found in the lymphocytes confirmed the diagnosis of freemartinism for seven out of the nine subjects.

Item Type:Article
ID Code:4873
Uncontrolled Keywords:C-banding, intersex, sex chromosomes, sex determination, sheep
Subjects:Area 07 - Scienze agrarie e veterinarie > VET/10 Clinica ostetrica e ginecologia veterinaria
Area 05 - Scienze biologiche > BIO/18 Genetica
Divisions:001 Università di Sassari > 01 Dipartimenti > Patologia e clinica veterinaria
001 Università di Sassari > 01 Dipartimenti > Scienze biomediche
Publisher:Università degli studi di Firenze
Deposited On:18 Nov 2010 13:55

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