titoli, abstracts, parole chiave >>>
Activation of α1-adrenoceptors inhibits growth hormone secretion in humans

Fanciulli, Giuseppe and Tomasi, Paolo and Delitala, A. P. and Delitala, Giuseppe (2009) Activation of α1-adrenoceptors inhibits growth hormone secretion in humans. Experimental and Clinical Endocrinology & Diabetes, Vol. 117 (9), p. 460-462. eISSN 1439-3646. Article.

Full text not available from this repository.

DOI: 10.1055/s-0029-1202796

Abstract

In order to determine whether an α1-adrenergic mechanism is involved in the secretion of Growth Hormone (GH) in humans, we studied the effect of the α1-adrenergic-stimulating agent methoxamine on serum GH levels in twelve normal males (age range 22-32 years). Intravenous infusion of methoxamine (dose: 6 μg/kg/min; duration: 150 min) significantly reduced serum GH levels at time 120 and 150, and on integrated concentrations. These data suggest that α1-adrenergic receptors inhibit tonic GH secretion in humans.

Item Type:Article
ID Code:4858
Status:Published
Refereed:Yes
Uncontrolled Keywords:α1-adrenoceptors, growth hormone, humans, hypothalamus, methoxamine
Subjects:Area 06 - Scienze mediche > MED/13 Endocrinologia
Area 06 - Scienze mediche > MED/09 Medicina interna
Divisions:001 Università di Sassari > 03 Istituti > Clinica medica generale e terapia medica
Publisher:Thieme
eISSN:1439-3646
Deposited On:16 Nov 2010 13:27

I documenti depositati in UnissResearch sono protetti dalle leggi che regolano il diritto d'autore

Repository Staff Only: item control page