Pinna, Antonio <1963- > and Carta, Adolfo and Demontis, Simonetta and Dore, Stefano and Carta, Francesco (2004) Neuro-ophthalmological findings in neurofibromatosis type 1. Neuro-Ophthalmology, Vol. 28 (5-6), p. 251-258. eISSN 1744-506X. Article.
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Objectives: To describe the neuro-ophthalmological findings in five patients with neurofibromatosis type 1 (NF-1). Methods: Retrospective case series. Results: Five patients (3 males, 2 females) with NF-1 who showed neuro-ophthalmogical findings were included in this study. Their ages ranged from one to 28 years (mean: 8 years).Two patients had glioma of the optic chiasm, one glioma of the optic nerve, one orbitotemporal plexiform neurofibroma and glioma of the optic chiasm, and one absence of the greater sphenoid wing. Conclusions: Patients with NF-1 may show different neuro-ophthalmological findings. Lesions tend to develop early in life and might have a favorable long-term natural history. Given the potential for serious visual loss, close follow-up until adolescence is recommended.
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