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Neuro-ophthalmological findings in neurofibromatosis type 1

Pinna, Antonio <1963- > and Carta, Adolfo and Demontis, Simonetta and Dore, Stefano and Carta, Francesco (2004) Neuro-ophthalmological findings in neurofibromatosis type 1. Neuro-Ophthalmology, Vol. 28 (5-6), p. 251-258. eISSN 1744-506X. Article.

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DOI: 10.1080/01658100490887896


Objectives: To describe the neuro-ophthalmological findings in five patients with neurofibromatosis type 1 (NF-1). Methods: Retrospective case series. Results: Five patients (3 males, 2 females) with NF-1 who showed neuro-ophthalmogical findings were included in this study. Their ages ranged from one to 28 years (mean: 8 years).Two patients had glioma of the optic chiasm, one glioma of the optic nerve, one orbitotemporal plexiform neurofibroma and glioma of the optic chiasm, and one absence of the greater sphenoid wing. Conclusions: Patients with NF-1 may show different neuro-ophthalmological findings. Lesions tend to develop early in life and might have a favorable long-term natural history. Given the potential for serious visual loss, close follow-up until adolescence is recommended.

Item Type:Article
ID Code:4833
Uncontrolled Keywords:Neurofibromatosis type 1, optic pathway gliomas, orbitotemporal plexiform neurofibroma, greater sphenoid wing absence, hyperthyroidism
Subjects:Area 06 - Scienze mediche > MED/30 Malattie apparato visivo
Divisions:001 Università di Sassari > 03 Istituti > Oftalmologia, Otorinolaringoiatria e Urologia
Publisher:Informa Healthcare
Deposited On:15 Nov 2010 14:34

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