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A Tutorial for microarray data analysis with SAS-STAT software

Dimauro, Corrado and Macciotta, Nicolò Pietro Paolo (2010) A Tutorial for microarray data analysis with SAS-STAT software. Current Bioinformatics, Vol. 5 (2), p. 89-108. ISSN 1574-8936. Article.

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DOI: 10.2174/157489310791268441

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Abstract

In recent years, microarrays have become a key experimental tool, enabling the analysis of genome-wide patterns of gene expression. Numerous complex statistical problems arise during the analysis of microarray data and, therefore, only specialized statisticians are able to extract the expressed genes. This tutorial is aimed to help biologists to conduct some, also if rough, analysis of their microarray data immediately afterwards they are produced. After a short review on statistical challenges in microarray studies, complete data analysis, from raw data to differentially expressed genes, was developed using both simulated and real data set. The referring microarray platform was the spotted cDNA microarray and all the computations were developed using the SAS-STAT software.

Item Type:Article
ID Code:4782
Status:Published
Refereed:Yes
Uncontrolled Keywords:Statistics, microarray, tutorial, cDNA microarray, data analysis
Subjects:Area 07 - Scienze agrarie e veterinarie > AGR/17 Zootecnica generale e miglioramento genetico
Area 07 - Scienze agrarie e veterinarie > AGR/19 Zootecnica speciale
Divisions:001 Università di Sassari > 01 Dipartimenti > Scienze zootecniche
Publisher:Bentham Science Publishers
ISSN:1574-8936
Deposited On:08 Nov 2010 12:39

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