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Induction of hypericins in Hypericum perforatum in response to chromium

Tirillini, Bruno and Ricci, Antonio and Pintore, Giorgio Antonio Mario and Chessa, Mario and Sighinolfi, Simona (2006) Induction of hypericins in Hypericum perforatum in response to chromium. Fitoterapia, Vol. 77 (3), p. 164-170. ISSN 0367-326X. Article.

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DOI: 10.1016/j.fitote.2006.01.011


Seedlings of Hypericum perforatum were grown with 0.01 and 0.1 mM of chromium added to the nutrient media. A treatment with 0.01 mM Cr(VI) for seven days resulted in an increased production of protopseudohypericin (+ 135%), hypericin (+ 38%) and pseudohypericin (+ 5%). Treatment with 0.1 mM Cr(VI) for two days also caused an increase of protopseudohypericin (+ 167%), hypericin (25%) and pseudohypericin (+ 5%). The greatest effect of chromium treatment was observed at a concentration of 0.1 mM for seven days: protopseudohypericin increased + 404% and pseudohypericin to + 379%. Hypericin was not affected by this treatment.

Item Type:Article
ID Code:4707
Uncontrolled Keywords:Hypericum perforatum, St. John's wort, chromium, hypericin, pseudohypericin, protopseudohypericin
Subjects:Area 05 - Scienze biologiche > BIO/15 Biologia farmaceutica
Divisions:001 Università di Sassari > 01 Dipartimenti > Farmaco, chimico, tossicologico
Deposited On:18 Oct 2010 17:15

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