Tirillini, Bruno and Ricci, Antonio and Pintore, Giorgio Antonio Mario and Chessa, Mario and Sighinolfi, Simona (2006) Induction of hypericins in Hypericum perforatum in response to chromium. Fitoterapia, Vol. 77 (3), p. 164-170. ISSN 0367-326X. Article.
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Seedlings of Hypericum perforatum were grown with 0.01 and 0.1 mM of chromium added to the nutrient media. A treatment with 0.01 mM Cr(VI) for seven days resulted in an increased production of protopseudohypericin (+ 135%), hypericin (+ 38%) and pseudohypericin (+ 5%). Treatment with 0.1 mM Cr(VI) for two days also caused an increase of protopseudohypericin (+ 167%), hypericin (25%) and pseudohypericin (+ 5%). The greatest effect of chromium treatment was observed at a concentration of 0.1 mM for seven days: protopseudohypericin increased + 404% and pseudohypericin to + 379%. Hypericin was not affected by this treatment.
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