Montisci, Roberta and Ruscazio, Massimo and Vacca, Alessandra and Garau, Pietro and Passiu, Giuseppe and Mathieu, Alessandro and Iliceto, Sabino and Meloni, Luigi (2004) Regional wall motion abnormalities during dobutamine stress echocardiography in patients with systemic sclerosis. Journal of the American College of Cardiology, Vol. 43 (5, Suppl. 2), p. A360. ISSN 0735-1097. Article.
Full text not available from this repository.
Background: Systemic sclerosis (SSc) is a chronic connective tissue disorder of
unknown etiology, characterized by cutaneous and visceral involvement.The pathogenesis
of the cardiac lesion in SSc is controversial, but the primary disorder of microvasculature
with diffuse arteriolar and capillary lesions could precede any fibrosis, thus causing
ischemic disorder to the heart. Dobutamine stress echocardiography (DSE) is a sensitive
predictor of coronary artery disease. This study was performed to assess the value of
DSE for noninvasive diagnosis of cardiac involvement in patients with SSc without clinical
evidence of heart disease and to determine if abnormal responses to dobutamine can be
explained by a decreased coronary flow velocity reserve (CFVR).
I documenti depositati in UnissResearch sono protetti dalle leggi che regolano il diritto d'autore
Repository Staff Only: item control page