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Visibility of tumor-like details in inline phase contrast mammography using quasimonochromatic X-ray sources

Golosio, Bruno and Delogu, Pasquale and Zanette, Irene and Oliva, Piernicola and Stefanini, Arnaldo and Stegel, Giovanni and Carpinelli, Massimo (2009) Visibility of tumor-like details in inline phase contrast mammography using quasimonochromatic X-ray sources. Nuclear Instruments and Methods in Physics Research. Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 608 (1, suppl. 1), S66-S69. ISSN 0168-9002. Article.

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DOI: 10.1016/j.nima.2009.05.037

Abstract

A new generation of quasimonochromatic high-flux X-ray sources, based on the X-ray radiation produced through Compton scattering between an electron beam and a laser beam, is under development. One of the possible applications of this source is inline phase contrast mammography, based on the observation of the edge-enhancement effect that can be observed at the border of structures inside the breast in images produced using a partially or totally coherent X-ray beam. In this work we present the results of a set of simulations of inline phase contrast mammography using typical inverse Compton scattering sources parameters. The simulated sample was a tumour-like mass having spherical shape, diameter between 200 μm and 5 mm, placed inside a breast-like matrix, 4 cm thick, and a standard composition of 50% glandular tissue and 50% adipose tissue. We discuss the minimum requirements for mammography using inverse Compton scattering sources and we discuss how the working parameters of the experimental setup (focal spot size, source-object distance, object-detector distance, detector point spread function, mean energy, energy bandwidth) affect the image quality, and specifically the edge-enhancement visibility. In particular, we show that the energy bandwidth does not significantly affect the visibility up to several keV. On the other hand, the edge-enhancement visibility depends substantially on other parameters such as source-object distance and detector point spread function. B. Golosioa, , , P. Delogub, I. Zanetteb, P. Olivaa, A. Stefaninib, G. Stegela and M. Carpinelli

Item Type:Article
ID Code:4489
Status:Published
Refereed:Yes
Uncontrolled Keywords:X-ray phase contrast imaging, inverse compton scattering, compact x-ray sources
Subjects:Area 01 - Scienze matematiche e informatiche > MAT/05 Analisi matematica
Area 02 - Scienze fisiche > FIS/07 Fisica applicata (a beni culturali, ambientali, biologia e medicina)
Divisions:001 Università di Sassari > 03 Istituti > Matematica e fisica
Publisher:North Holland / Elsevier
ISSN:0168-9002
Additional Information:Paper presented at the Workshop on “Compton Sources for X/γ Rays: Physics and Applications”, held on September 7–12, 2008, in Porto Conte, Sardinia, Italy.
Deposited On:03 Sep 2010 11:53

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