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A case of coexistence between JAK2V617F and BCR/ABL

Pardini, Simonetta and Fozza, Claudio and Contini, Salvatore and Rimini, Elena and Ottaviani, Emanuela E. and Amabile, Marilina and Rosti, Gianantonio and Longinotti, Maurizio Roberto (2008) A case of coexistence between JAK2V617F and BCR/ABL. European Journal of Haematology, Vol. 81 (1), p. 75-76. eISSN 1600-0609. Article.

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DOI: 10.1111/j.1600-0609.2008.01063.x


Very recently the JAK2V617F mutation has been described in BCR⁄ABL+ patients for the first time. Even though characterized by very different clinical patterns, these cases raise some questions about the biological meaning of the coexistence between these disease-specific molecular markers.
The present report confirms that the unexpected coexistence between these two disease-specific molecular markers - the JAK2V617F mutation and the BCR⁄ABL translocation - is possible.

Item Type:Article
ID Code:4485
Uncontrolled Keywords:JAK2V617F mutation, BCR-ABL positive, myelogenous, melofibrosis, leukemia
Subjects:Area 06 - Scienze mediche > MED/15 Malattie del sangue
Divisions:001 Università di Sassari > 03 Istituti > Ematologia
Publisher:Blackwell / Wiley
Copyright Holders:© 2008 The Authors, Journal compilation 81 (75–76) © 2008 Blackwell Munksgaard
Deposited On:03 Sep 2010 12:02

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