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Chemical composition and antimicrobial activity of Rosmarinus officinalis L. oils from Sardinia and Corsica

Pintore, Giorgio Antonio Mario and Usai, Marianna and Bradesi, Pascale and Juliano, Claudia Clelia Assunta and Boatto, Gianpiero and Tomi, Felix and Chessa, Mario and Cerri, Riccardo and Casanova, Joseph (2002) Chemical composition and antimicrobial activity of Rosmarinus officinalis L. oils from Sardinia and Corsica. Flavour and Fragrance Journal, Vol. 17 (1), p. 15-19. ISSN 0882-5734. Article.

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DOI: 10.1002/ffj.1022

Abstract

A detailed analysis of Rosmarinus officinalis L. essential oil from Sardinia and Corsica (α-pinene/verbenone/bornyl acetate chemotype) was carried out using GC-RI, GC-MS and 13C-NMR, on the bulk sample or after repeated chromatography. Fifty-eight compounds were identified. The antimicrobial activity of two Sardinian samples was investigated and both exhibited a moderate antibacterial activity. Gram-positive bacteria were more sensitive (MIC 2.5-4 mg/ml) than Gram-negative bacteria. Killing time experiments demonstrated that prolonged times (60 min) are needed to completely inactivate the bacterial inoculum.

Item Type:Article
ID Code:4463
Status:Published
Refereed:Yes
Uncontrolled Keywords:Rosmarinus officinalis L., essential oil composition, GC–MS; 13C-NMR, antimicrobial activity
Subjects:Area 03 - Scienze chimiche > CHIM/09 Farmaceutico tecnologico applicativo
Area 05 - Scienze biologiche > BIO/15 Biologia farmaceutica
Divisions:001 Università di Sassari > 01 Dipartimenti > Farmaco, chimico, tossicologico
001 Università di Sassari > 01 Dipartimenti > Scienze del farmaco
Publisher:Wiley
ISSN:0882-5734
Copyright Holders:© 2001 John Wiley & Sons, Ltd.
Deposited On:01 Sep 2010 15:40

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