Fato, Romana and Bergamini, Christian and Leoni, Serena and Pinna, Antonio <1963- > and Carta, Francesco and Cardascia, Nicola and Micelli Ferrari, Tommaso and Sborgia, Carlo and Lenaz, Giorgio (2010) Coenzyme Q10 vitreous levels after administration of coenzyme Q10 eyedrops in patients undergoing vitrectomy. Acta Ophthalmologica Scandinavica, Vol. 88 (4), p. 150-151. eISSN 1600-0420. Article.
Full text not available from this repository.
Coenzyme Q (ubiquinone, CoQ10) is an essential electron carrier in the mitochondrial respiratory chain. It is located mainly in the inner mitochondrial membrane, but is also present in serum lipoproteins, endomembranes and the plasma membrane of eukaryotic cells (Turunen et al. 2004). CoQ10 is also a redox component of electron transport chains in extramitochondrial membranes, where it acts as a powerful antioxidant and membrane stabilizer. Indirect evidence also points out that CoQ10 may be a useful therapeutic agent in ocular diseases where oxidative stress and apoptotic cell death are important pathogenic factors (Dunlop & Dunlop 1995; Blasi et al. 2001). The purpose of this study was to assess the intraocular penetration of CoQ10 by determining its vitreous concentration in patients treated with a commercially available topical eye preparation (Coqun® eyedrops; Visufarma SpA, Rome, Italy) and in untreated patients.
I documenti depositati in UnissResearch sono protetti dalle leggi che regolano il diritto d'autore
Repository Staff Only: item control page