Patteri, Pierpaolo and Serru, Alain and Chessa, Maria Letizia and Loi, Michele and Pinna, Antonio <1963- > (2009) Recurrent giant chalazia in hyperimmunoglobulin E (Job’s) syndrome. International Ophthalmology, Vol. 29 (5), p. 415-417. eISSN 1573-2630. Article.
Full text not available from this repository.
Hyperimmunoglobulinemia E (Job’s) syndrome is a rare autosomal dominant disorder appearing early in life with recurrent skin and pulmonary infections, characterized by markedly increased serum immunoglobulin E (IgE) levels. We describe a 50-year-old man with a 4-year history of recurrent, multiple giant chalazia in all eyelids. Medications and surgical intervention had produced only transient improvement. The patient had also had pulmonary and scalp infection. Laboratory tests disclosed elevated serum IgE (>1,000 IU/ml) and eosinophilia. As a result, based on the patient’s history and clinical and laboratory findings, a diagnosis of Job’s syndrome was made. Even though rarely, recurrent multiple giant chalazia may occur as an ophthalmic feature of Job’s syndrome. Hyperimmunoglobulinemia E syndrome should be suspected in any case of recurrent giant chalazia, regardless of the patient’s age. Measurement of serum IgE and eosinophils, along with internal evaluation, is essential to establish a proper diagnosis.
I documenti depositati in UnissResearch sono protetti dalle leggi che regolano il diritto d'autore
Repository Staff Only: item control page