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Cardenolides content in wild Sardinian Digitalis purpurea L. populations

Usai, Marianna and Atzei, Aldo Domenico and Marchetti, Mauro (2007) Cardenolides content in wild Sardinian Digitalis purpurea L. populations. Natural Product Research, Vol. 21 (9), p. 798-804. eISSN 1478-6427. Article.

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DOI: 10.1080/14786410701218291


In order to quantify the amounts of digitoxigenin and gitoxigenin in wild Sardinian Digitalis purpurea L. an easy extraction method and an high performance liquid chromatography (HPLC) analytical technique have been set up. The analyzed samples, stemming from six different locations, showed a great variability in glycoside content. The HPLC analyses carried out on 2-year-old plants of D. purpurea showed that the amounts of digitoxigenin and gitoxigenin ranged between 11.34 and 240.59 mg kg-1 and 4.05 and 178.07 mg kg-1, respectively, calculated on fresh material. Chemometric analyses, carried out considering different morphological characters, showed that correlations between morphological variations and glycoside content are poor.

Item Type:Article
ID Code:4357
Uncontrolled Keywords:Cardenolides, Digitalis purpurea L, digitoxigenin, gitoxigenin, principal component analysis, scrophulariaceae
Subjects:Area 05 - Scienze biologiche > BIO/15 Biologia farmaceutica
Divisions:002 Altri enti e centri di ricerca del Nord Sardegna > CNR-Consiglio Nazionale delle Ricerche > Istituto di chimica biomolecolare, Sassari
001 Università di Sassari > 01 Dipartimenti > Scienze del farmaco
Publisher:Taylor & Francis
Deposited On:24 Aug 2010 16:21

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